Antimicrobial constituents from the tubers of Bletilla ochracea

Planta Med. 2012 Apr;78(6):606-10. doi: 10.1055/s-0031-1298264. Epub 2012 Mar 1.

Abstract

A new 2-(2-methylpropyl)butanedioic acid derivative, bletillin A ( 1), and a new bibenzyl, bletillin B ( 2), together with seventeen known compounds ( 3- 19), were isolated from the tubers of Bletilla ochracea Schltr. Their structures were established by detailed spectroscopic analyses. Phenanthrenes ( 12- 14) exhibited antibacterial activities against gram-positive bacteria Staphylococcus aureus, S. epidermidis, and Bacillus subtilis, with MIC values of 12.5-25 µg/mL.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Bacillus subtilis / drug effects
  • Bibenzyls / chemistry
  • Bibenzyls / isolation & purification
  • Bibenzyls / pharmacology*
  • Biological Assay
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Orchidaceae / chemistry*
  • Phenanthrenes / chemistry
  • Phenanthrenes / isolation & purification
  • Phenanthrenes / pharmacology*
  • Plant Tubers / chemistry
  • Plants, Medicinal / chemistry
  • Staphylococcus aureus / drug effects
  • Staphylococcus epidermidis / drug effects

Substances

  • Anti-Bacterial Agents
  • Bibenzyls
  • Drugs, Chinese Herbal
  • Phenanthrenes
  • bletillin A
  • bletillin B