The use of porcine acellular dermal matrix in silicone implant-based breast reconstruction

Arch Gynecol Obstet. 2012 Jul;286(1):187-92. doi: 10.1007/s00404-012-2266-x. Epub 2012 Mar 2.

Abstract

Introduction: The most frequently occurring long-term complication in implant-based breast reconstruction is fibrotic capsule formation at the recipient site, with concurrent dysesthesia and poor aesthetic results. Using porcine acellular dermal matrix (PADM) as a connective tissue graft material is supposed to improve the quality and quantity of soft tissue in implant-based breast reconstruction. This study investigates the indications for and the results and the costs of using PADM for the correction or prevention of implant-associated breast deformities.

Materials and methods: This study reviewed a single surgeon's experience in the correction or prevention of implant-associated breast deformities with PADM in breast cancer-related breast reconstruction from 2009 to 2011. A total of 23 patients (27 breasts) were included in the study. The aesthetic outcome, the incidence and the type of complication were analysed. Twenty-three women underwent breast cancer-related breast reconstruction: 19 women underwent single-breast reconstruction and four women underwent bilateral reconstruction.

Results: Of the 23 patients who underwent breast reconstruction, 18 (78%) were "satisfied" with the aesthetic and haptic outcome after implant-based reconstruction with PADM. One patient (one breast) required another breast operation because of ipsilateral breast cancer recurrence during the follow-up period. PADM-assisted implant-based breast reconstruction has a satisfactory safety profile.

Conclusion: The use of PADM as an interface matrix for implant-based breast reconstruction yielded predictable and acceptable aesthetic and haptic results by preventing capsular contracture, rippling, implant malposition, soft-tissue thinning and failure of the silicone implant-based breast augmentation.

MeSH terms

  • Adult
  • Aged
  • Animals
  • Biocompatible Materials
  • Breast Implants* / adverse effects
  • Breast Neoplasms / surgery
  • Esthetics
  • Female
  • Humans
  • Mammaplasty / adverse effects
  • Mammaplasty / methods*
  • Mastectomy
  • Middle Aged
  • Patient Satisfaction*
  • Silicones
  • Skin, Artificial*
  • Swine
  • Tissue Scaffolds
  • Touch

Substances

  • Biocompatible Materials
  • Silicones