The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals. Part I

Contact Dermatitis. 2012 Apr:66 Suppl 1:11-24. doi: 10.1111/j.1600-0536.2011.02004_2.x.

Abstract

To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'.

Publication types

  • Review

MeSH terms

  • Allergens / toxicity*
  • Animals
  • Consumer Product Safety*
  • Dermatitis, Allergic Contact / etiology*
  • Dermatitis, Allergic Contact / prevention & control
  • Dermatitis, Occupational / etiology
  • Dermatitis, Occupational / prevention & control
  • Europe
  • Humans
  • Skin Tests / methods*

Substances

  • Allergens