Target-selective photodegradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by designed fullerene-sugar hybrids

Chem Asian J. 2012 May;7(5):911-4. doi: 10.1002/asia.201101043. Epub 2012 Feb 29.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrates / chemistry
  • Carbohydrates / pharmacology
  • Cell Line
  • Fullerenes / chemistry*
  • Fullerenes / pharmacology*
  • HIV Infections / drug therapy
  • HIV Infections / radiotherapy
  • HIV Protease / chemistry
  • HIV Protease / metabolism*
  • HIV Protease Inhibitors / chemistry*
  • HIV Protease Inhibitors / pharmacology*
  • HIV-1 / drug effects
  • HIV-1 / enzymology*
  • HIV-1 / radiation effects
  • Humans
  • Leukocytes, Mononuclear / virology
  • Light
  • Models, Molecular
  • Photolysis
  • T-Lymphocytes / virology
  • Ultraviolet Rays

Substances

  • Carbohydrates
  • Fullerenes
  • HIV Protease Inhibitors
  • HIV Protease
  • p16 protease, Human immunodeficiency virus 1