Application of optical imaging and spectroscopy to radiation biology

Radiat Res. 2012 Apr;177(4):365-75. doi: 10.1667/rr2531.1. Epub 2012 Feb 23.

Abstract

Optical imaging and spectroscopy is a diverse field that has been of critical importance in a wide range of areas in radiation research. It is capable of spanning a wide range of spatial and temporal scales, and has the sensitivity and specificity needed for molecular and functional imaging. This review will describe the basic principles of optical imaging and spectroscopy, highlighting a few relevant applications to radiation research.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Cell Hypoxia
  • Cell Tracking / methods
  • Fiber Optic Technology / methods
  • Fluorometry / methods
  • Genes, Reporter
  • Humans
  • Luminescent Measurements / methods
  • Luminescent Proteins / analysis
  • Microscopy / methods
  • Molecular Imaging / methods*
  • Neoplasms / chemistry
  • Neoplasms / pathology
  • Neoplasms / radiotherapy
  • Neoplasms, Experimental / chemistry
  • Neoplasms, Experimental / pathology
  • Optical Phenomena*
  • Oxyhemoglobins / analysis
  • Photoacoustic Techniques
  • Radiobiology / methods*
  • Scattering, Radiation
  • Spectrum Analysis / methods*
  • Tomography / methods
  • Tomography, Optical Coherence / methods

Substances

  • Luminescent Proteins
  • Oxyhemoglobins