[Morphine addiction in non-human primates using rhesus monkeys]

Dongwuxue Yanjiu. 2012 Feb;33(1):89-91. doi: 10.3724/SP.J.1141.2012.01089.
[Article in Chinese]

Abstract

We showed that rhesus monkeys (Macaca mulatta) can develop a morphine dependence. Rhesus monkeys successfully established a conditioned place preference (CPP) induced by morphine treatment and this preference lasted for at least (36.3 ± 1.3) months. This animal model may be useful for research into addiction in humans.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Conditioning, Operant / drug effects*
  • Disease Models, Animal*
  • Humans
  • Macaca mulatta*
  • Morphine / adverse effects*
  • Morphine Dependence / etiology
  • Morphine Dependence / psychology*

Substances

  • Morphine