Mechanical cardiac support systems represent rapidly developing segment of current cardiology. Several support systems have been recently introduced into the clinical practice for the therapy of cardiogenic shock or refractory non-tolerated ventricular tachycardia, for the support of high-risk catheter interventions, and even for the support of cardiopulmonary resuscitation. These new technologies enable quick set-up and introduction even in emergency situations and may be used not only as a ventricular assist device but also as a replacement of seriously damaged heart function. At the present time, number of centers have several different mini-invasive cardiac support systems at disposal in specific patients. This paper is a brief overview of the currently available mini-invasive mechanical cardiac support systems and describes their advantages and disadvantages.