Technical and clinical long-term results of infrapopliteal percutaneous transluminal angioplasty for critical limb ischemia

J Vasc Interv Radiol. 2012 Apr;23(4):461-7, 467.e1. doi: 10.1016/j.jvir.2011.12.011. Epub 2012 Feb 1.

Abstract

Purpose: To evaluate the technical success and clinical long-term effectiveness of percutaneous transluminal angioplasty (PTA) of the infrapopliteal arteries in critical limb ischemia (CLI) and to determine if total vessel dilation (TVD) increases the limb salvage rate (LSR).

Materials and methods: A retrospective study was performed in 90 consecutive patients (35 men and 55 women, median age 79 years, standard deviation [SD] 9 years) over a 5.5-year period to determine the effectiveness of infrapopliteal PTA in treating CLI. Of 90 patients, 61 underwent TVD. Analysis of LSR was performed using the Kaplan-Meier life-table analysis.

Results: In 90 limbs, there were 57 infrapopliteal stenoses and 104 occlusions. Including 10 technical failures (TF) (TF = 11%), LSR at 1 year and 3 years for all 90 patients with previously untreated lesions was 78%. For 80 technically successful (TS) procedures (TS = 89%), LSR at 1 year and 3 years was 87%. At 1 year and 3 years, LSR for the 61 patients who had TVD was 89%. In all patients, there were no amputations after the first year. The 30-day mortality rate was 7%.

Conclusions: PTA of the infrapopliteal arteries appears to be an effective treatment for patients with CLI. TVD provides an improved LSR and warrants additional evaluation.

MeSH terms

  • Aged
  • Angioplasty / methods*
  • Angioplasty / mortality*
  • Humans
  • Ischemia / diagnostic imaging
  • Ischemia / mortality*
  • Ischemia / surgery*
  • Leg / blood supply*
  • Limb Salvage / mortality*
  • Longitudinal Studies
  • Netherlands / epidemiology
  • Popliteal Artery / diagnostic imaging
  • Popliteal Artery / surgery*
  • Prevalence
  • Radiography
  • Risk Assessment
  • Risk Factors
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome