The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut

Hergen Spits; Jenny Mjösberg

doi:10.1016/j.immuni.2012.01.004

The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut

Immunity. 2012 Jan 27;36(1):5-7. doi: 10.1016/j.immuni.2012.01.004.

Authors

Hergen Spits¹, Jenny Mjösberg

Affiliation

¹ Tytgat Institute of Intestinal and Liver Research at the Academic Medical Center, Amsterdam, The Netherlands. hergen.spits@amc.uva.nl

PMID: 22284414
DOI: 10.1016/j.immuni.2012.01.004

Abstract

Innate lymphoid cells (ILCs) regulate the epithelial barrier function and immunity in the gut. How ILC numbers are maintained is unknown. In this issue of Immunity, Qiu et al. (2012) report that the transcription factor aryl hydrocarbon receptor controls survival and function of gut-residing ILCs.

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