Marked response to both S-1 and pemetrexed in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinoma

Acta Oncol. 2012 Sep;51(7):942-4. doi: 10.3109/0284186X.2011.653827. Epub 2012 Jan 27.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adenocarcinoma / chemistry*
  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma of Lung
  • Adult
  • Anaplastic Lymphoma Kinase
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Biomarkers, Tumor / analysis*
  • Cell Cycle Proteins / analysis*
  • Drug Combinations
  • Glutamates / therapeutic use*
  • Guanine / analogs & derivatives*
  • Guanine / therapeutic use
  • Humans
  • Lung Neoplasms / chemistry*
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / drug therapy*
  • Male
  • Microtubule-Associated Proteins / analysis*
  • Oxonic Acid / therapeutic use*
  • Pemetrexed
  • Positron-Emission Tomography
  • Receptor Protein-Tyrosine Kinases / analysis*
  • Serine Endopeptidases / analysis*
  • Tegafur / therapeutic use*
  • Treatment Outcome

Substances

  • Antimetabolites, Antineoplastic
  • Biomarkers, Tumor
  • Cell Cycle Proteins
  • Drug Combinations
  • Glutamates
  • Microtubule-Associated Proteins
  • Pemetrexed
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid
  • Guanine
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases
  • EML4 protein, human
  • Serine Endopeptidases