Case for diagnosis. Benign cephalic histiocytosis

An Bras Dermatol. 2011 Nov-Dec;86(6):1222-5. doi: 10.1590/s0365-05962011000600031.
[Article in English, Portuguese]

Abstract

The present paper reports a case of benign cephalic histiocytosis in a 15-month baby boy, who developed multiple papules bilaterally in the malar region with no other associated manifestations. Histopathology revealed a papillary dermal pattern, while immunohistochemistry was negative for S100 and CD1a and positive for CD68. Therefore, diagnosis was established as non-Langerhans cell histiocytosis, based on the clinical, histopathological and immunohistochemical features present.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD / immunology*
  • Antigens, Differentiation, Myelomonocytic / immunology*
  • Diagnosis, Differential
  • Histiocytosis, Non-Langerhans-Cell / immunology
  • Histiocytosis, Non-Langerhans-Cell / pathology*
  • Humans
  • Immunohistochemistry
  • Infant
  • Male

Substances

  • Antigens, CD
  • Antigens, Differentiation, Myelomonocytic
  • CD68 antigen, human