Ex vivo models of HIV sexual transmission and microbicide development

Curr HIV Res. 2012 Jan 1;10(1):73-8. doi: 10.2174/157016212799304661.

Abstract

Here, we review the armamentarium on in vitro/ex vivo models of HIV sexual transmission and discuss how these models can be applied to study candidate microbicides.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Intravaginal
  • Administration, Rectal
  • Anti-Infective Agents, Local / administration & dosage
  • Anti-Infective Agents, Local / therapeutic use*
  • Anti-Retroviral Agents / administration & dosage
  • Anti-Retroviral Agents / therapeutic use*
  • Cells, Cultured / drug effects
  • Drug Design
  • Epithelial Cells / drug effects
  • HIV Infections / prevention & control*
  • HIV Infections / transmission*
  • HIV-1*
  • Humans
  • Models, Biological

Substances

  • Anti-Infective Agents, Local
  • Anti-Retroviral Agents