The objective of this quantitative study was to identify stressing factors, level of stress in nurses, overall health conditions, and coping strategies used by nurses in the working environment. Data collection was performed using three instruments: a survey for daily activities, an inventory of coping strategies, and an inventory for overall health conditions. The population of this study was composed by 143 nurses, most of them with a low level of stress (55.25%) and with a regular health condition (50.35%). Regarding coping forms, problem solving was the factor of highest average. In conclusion, educational actions must be encouraged with an aim to offer tools for professionals to develop coping strategies in their everyday activities, thus minimizing the effect of stress on their health conditions and at work.