Typical and atypical carcinoid tumors of lung: a clinicopathologic and DNA analysis of 20 tumors

Mod Pathol. 1990 Jul;3(4):502-7.

Abstract

Twelve typical carcinoid tumors (TCT) and eight atypical (malignant) carcinoid tumors (ACT) of the lung were studied for quantitative DNA content by image analysis in order to identify prognostic features. No correlation of any histologic variables of the TCTs and ACTs with abnormal DNA content were noted. Furthermore, it was concluded that although abnormalities of DNA content, particularly aneuploidy, are common in ACTs, DNA ploidy cannot be used independently to assess malignant potential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Carcinoid Tumor / genetics
  • Carcinoid Tumor / pathology*
  • DNA, Neoplasm / analysis*
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology*
  • Male
  • Middle Aged
  • Ploidies
  • Prognosis
  • Retrospective Studies

Substances

  • DNA, Neoplasm