The Arabo-Islamic migrations in Madagascar: first genetic study of the GM system in three Malagasy populations

Int J Immunogenet. 2012 Apr;39(2):161-9. doi: 10.1111/j.1744-313X.2011.01069.x. Epub 2011 Dec 14.

Abstract

The Antemoro are an ethnic group from the southeast coast of Madagascar who claims an Arab origin. Cultural signatures of an Arabo-Islamic influence have been found in this region. Nevertheless, their origins are very contentious. Through this study, we want to determine whether this ethnic group had a particular GM profile that differentiated it from other Malagasy populations, and whether there were detectable genetic traces of the Arabo-Islamic migration. The Gm polymorphisms of IgG immunoglobulins was analysed in a population of Antemoro (N = 85), two other Malagasy populations from northern Fihereňa (N = 82) and southern Fihereňa (N = 50) and in a Comorian population (N = 171). This last group was used to enlarge the database for genetic comparisons. Results revealed significant contributions from Africa (60%, 0.092 ≤F(ST) ≤ 0.280) and Southeast Asia (40%, 0.043 ≤ F(ST) ≤ 0.590) to the Antemoro genetic pool. No direct genetic relationships with the Middle East. These results bring new insights into the population history of Madagascar.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabs / genetics*
  • Computational Biology
  • Databases, Factual
  • Emigration and Immigration*
  • Gene Frequency
  • Genetic Testing
  • Genetic Variation
  • Genetics, Population*
  • Haplotypes
  • Humans
  • Immunoglobulin Gm Allotypes / blood
  • Immunoglobulin Gm Allotypes / genetics*
  • Madagascar / ethnology
  • Phenotype
  • Population Surveillance

Substances

  • Immunoglobulin Gm Allotypes