Influence of age, sex, and haplotypes of thiopurine methyltransferase (TPMT) gene on 6- mercaptopurine toxicity in children with acute lymphoblastic leukemia

Eur J Clin Pharmacol. 2012 May;68(5):887-8; author reply 885-6. doi: 10.1007/s00228-011-1185-2. Epub 2011 Dec 14.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Antimetabolites, Antineoplastic / toxicity*
  • Female
  • Humans
  • Male
  • Mercaptopurine / toxicity*
  • Methyltransferases / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Pyrophosphatases / genetics*

Substances

  • Antimetabolites, Antineoplastic
  • Mercaptopurine
  • Methyltransferases
  • Pyrophosphatases