Corticosteroid therapy for liver abscess in chronic granulomatous disease

Clin Infect Dis. 2012 Mar 1;54(5):694-700. doi: 10.1093/cid/cir896. Epub 2011 Dec 9.

Abstract

Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.

Publication types

  • Case Reports
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use*
  • Granulomatous Disease, Chronic / complications*
  • Humans
  • Liver Abscess / complications*
  • Liver Abscess / diagnosis
  • Liver Abscess / drug therapy*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Adrenal Cortex Hormones
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents