Abstract
4.5 nm nanoceria particles are successfully encapsulated into the apoferritin cavity via a dissociation-reconstruction route. The apoferritin coating not only improves the biocompatibility and changes the cellular uptake route of nanoceria, but also manipulates the electron localization at the surface of the nanoparticle thereby ameliorating the ROS-scavenging activity.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Apoferritins / chemistry*
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Apoferritins / metabolism
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Biocompatible Materials / chemistry
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Biocompatible Materials / metabolism
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Cell Line, Tumor
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Cerium / chemistry*
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Cerium / metabolism
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Free Radical Scavengers / metabolism
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Humans
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Nanocomposites / chemistry*
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Oxidation-Reduction
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Particle Size
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Reactive Oxygen Species / metabolism
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Surface Properties
Substances
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Biocompatible Materials
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Free Radical Scavengers
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Reactive Oxygen Species
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Cerium
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ceric oxide
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Apoferritins