Apoferritin-CeO2 nano-truffle that has excellent artificial redox enzyme activity

Chem Commun (Camb). 2012 Mar 28;48(26):3155-7. doi: 10.1039/c1cc15815e. Epub 2011 Dec 1.

Abstract

4.5 nm nanoceria particles are successfully encapsulated into the apoferritin cavity via a dissociation-reconstruction route. The apoferritin coating not only improves the biocompatibility and changes the cellular uptake route of nanoceria, but also manipulates the electron localization at the surface of the nanoparticle thereby ameliorating the ROS-scavenging activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoferritins / chemistry*
  • Apoferritins / metabolism
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / metabolism
  • Cell Line, Tumor
  • Cerium / chemistry*
  • Cerium / metabolism
  • Free Radical Scavengers / metabolism
  • Humans
  • Nanocomposites / chemistry*
  • Oxidation-Reduction
  • Particle Size
  • Reactive Oxygen Species / metabolism
  • Surface Properties

Substances

  • Biocompatible Materials
  • Free Radical Scavengers
  • Reactive Oxygen Species
  • Cerium
  • ceric oxide
  • Apoferritins