Should multivisceral transplantation be considered in patients colonized with multidrug-resistant Pseudomonas aeruginosa?

Microb Drug Resist. 2012 Feb;18(1):74-8. doi: 10.1089/mdr.2011.0099. Epub 2011 Nov 22.

Abstract

This report describes two subsequent liver-small bowel-pancreas-kidney (multivisceral) transplantations in a child colonized with multidrug-resistant Pseudomonas aeruginosa. We discuss the dilemma concerning the transplantation of patients colonized with multidrug-resistant Pseudomonas spp., its potential consequences, and the peri and postoperative management of these patients.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Child, Preschool
  • Disease Management
  • Drug Resistance, Multiple, Bacterial
  • Female
  • Fluconazole / pharmacology
  • Fluconazole / therapeutic use
  • Humans
  • Intestine, Small / transplantation
  • Kidney Transplantation
  • Liver Transplantation
  • Organ Transplantation* / methods
  • Pancreas Transplantation
  • Penicillanic Acid / analogs & derivatives
  • Penicillanic Acid / pharmacology
  • Penicillanic Acid / therapeutic use
  • Piperacillin / pharmacology
  • Piperacillin / therapeutic use
  • Piperacillin, Tazobactam Drug Combination
  • Pseudomonas Infections / drug therapy*
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / growth & development
  • Pseudomonas aeruginosa / pathogenicity

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Piperacillin, Tazobactam Drug Combination
  • Penicillanic Acid
  • Fluconazole
  • Piperacillin