Patient-reported outcomes in adult survivors with single-ventricle physiology

Cardiology. 2011;120(1):36-42. doi: 10.1159/000333112. Epub 2011 Nov 17.

Abstract

Objectives: Data on patient-reported outcomes (PROs) in patients with single-ventricle physiology (SVP) are scarce. We sought (1) to describe the perceived health status, quality of life, symptoms of anxiety and depression, and sense of coherence in adult survivors with SVP, (2) to compare PROs across functional classes, and (3) to compare PROs between patients and controls.

Methods: A case-control study in two adult congenital heart programmes with 62 adult survivors with SVP were matched to 172 healthy controls. A wide range of PROs were measured using validated questionnaires. The treating physician classified patients according to the Ability Index.

Results: Patients with SVP have a good functional status. Patients in Ability Index class I consistently reported the best scores, similar to those of healthy controls. Negative associations were found between functional class and outcomes of perceived health and quality of life. For patients in Ability Index class II and III, PROs were poorer.

Conclusions: PROs in patients with SVP are generally good.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Anxiety Disorders / etiology
  • Case-Control Studies
  • Cross-Sectional Studies
  • Depressive Disorder / etiology
  • Female
  • Health Status
  • Heart Ventricles / abnormalities*
  • Heart Ventricles / surgery
  • Humans
  • Male
  • Patient Satisfaction
  • Perception
  • Quality of Life
  • Self Concept
  • Surveys and Questionnaires
  • Survivors*
  • Ventricular Dysfunction / psychology*
  • Ventricular Function / physiology*
  • Young Adult