Swarming motility and the control of master regulators of flagellar biosynthesis

Mol Microbiol. 2012 Jan;83(1):14-23. doi: 10.1111/j.1365-2958.2011.07917.x. Epub 2011 Nov 22.

Abstract

Swarming motility is the movement of bacteria over a solid surface powered by rotating flagella. The expression of flagellar biosynthesis genes is governed by species-specific master regulator transcription factors. Mutations that reduce or enhance master regulator activity have a commensurate effect on swarming motility. Here we review what is known about the proteins that modulate swarming motility and appear to act upstream of the master flagellar regulators in diverse swarming bacteria. We hypothesize that environmental control of the master regulators is important to the swarming phenotype perhaps at the level of controlling flagellar number.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Bacteria / genetics
  • Bacteria / metabolism*
  • Bacterial Physiological Phenomena*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Flagella / genetics
  • Flagella / metabolism*
  • Gene Expression Regulation, Bacterial*
  • Mutation

Substances

  • Bacterial Proteins