Abstract
A 60-year-old Ghanese woman was treated with radiotherapy and capecitabine for metastatic breast cancer. 6 weeks after starting capecitabine she developed palmar and plantar hyperpigmentation, which preceded symptoms of hand-foot syndrome, a known adverse effect of capecitabine. After a dose reduction, the hand-foot syndrome diminished but the hyperpigmentation remained. 8 months later the patient was well and stable.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Antimetabolites, Antineoplastic / adverse effects*
-
Antimetabolites, Antineoplastic / therapeutic use
-
Breast Neoplasms / drug therapy
-
Breast Neoplasms / radiotherapy
-
Capecitabine
-
Deoxycytidine / adverse effects
-
Deoxycytidine / analogs & derivatives*
-
Deoxycytidine / therapeutic use
-
Female
-
Fluorouracil / adverse effects
-
Fluorouracil / analogs & derivatives*
-
Fluorouracil / therapeutic use
-
Foot Dermatoses / chemically induced*
-
Hand Dermatoses / chemically induced*
-
Humans
-
Hyperpigmentation / chemically induced*
-
Middle Aged
Substances
-
Antimetabolites, Antineoplastic
-
Deoxycytidine
-
Capecitabine
-
Fluorouracil