Cerebellar haemorrhage in the extremely preterm infant

J Paediatr Child Health. 2012 Apr;48(4):350-5. doi: 10.1111/j.1440-1754.2011.02232.x. Epub 2011 Nov 14.

Abstract

Aim: The aim of this study was to investigate the incidence, risk factors and developmental outcomes of cerebellar haemorrhage in the extremely preterm infant.

Methods: Over a 4-year period from January 2004, all patients with cerebellar haemorrhage born at 24-27 weeks gestation or with a birthweight < 1000 g were identified from database review. All patients had cranial ultrasound scans including views from the mastoid fontanelle. To verify the incidence, a review of all reports over the 4-year period and a review of all cranial imaging over a 2-year period were carried out.

Results: From the data analysed on 339 neonates, five cases of cerebellar haemorrhage were identified, four on ultrasound scan (1.2%) and one on magnetic resonance imaging (1.5% total). Two cases were associated with grade III peri-intraventricular haemorrhage. The cases had diverse maternal, antenatal and post-natal risk factors. The two with associated peri-intraventricular haemorrhage have developmental delay. The cases with isolated cerebellar haemorrhage had good neurodevelopmental outcomes.

Conclusions: A low incidence of cerebellar haemorrhage identified from the mastoid fontanelle was demonstrated. The neurodevelopmental outcome was better than that described in previous reports.

MeSH terms

  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / epidemiology*
  • Cerebral Hemorrhage / etiology*
  • Cerebral Hemorrhage / physiopathology
  • Child Development / physiology*
  • Cranial Fossa, Posterior / blood supply
  • Cranial Fossa, Posterior / physiopathology
  • Databases, Factual
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Medical Audit
  • Premature Birth* / physiopathology
  • Ultrasonography