Abstract
Ruthenium-catalyzed isoquinolone syntheses with ample scope were accomplished through carboxylate assistance in environmentally benign water as a reaction medium. The high chemoselectivity of the ruthenium(II) carboxylate complex also set the stage for the direct use of free hydroxamic acids for annulations of alkynes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Benzamides / chemistry*
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Carboxylic Acids / chemistry
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Catalysis
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Colorimetry
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Isoquinolines / chemical synthesis*
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Isoquinolines / chemistry
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Molecular Structure
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Ruthenium / chemistry*
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Water / chemistry
Substances
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Alkynes
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Benzamides
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Carboxylic Acids
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Isoquinolines
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Water
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Ruthenium