Giant multilocular sex cord tumor with annular tubules associated with precocious puberty

Am J Obstet Gynecol. 2012 Jan;206(1):e14-6. doi: 10.1016/j.ajog.2011.09.025. Epub 2011 Sep 24.

Abstract

We report a case of sex cord tumor with annular tubules featuring a giant multilocular cyst, grossly similar to cystadenoma, in the ovary of an 8.5 year old girl. Estrogen-related symptoms, including precocious puberty and irregular uterine bleeding, immediately improved after tumor resection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Cystadenoma / complications
  • Cystadenoma / diagnosis*
  • Cystadenoma / surgery
  • Estrogens / blood
  • Female
  • Follicle Stimulating Hormone / blood
  • Gynecologic Surgical Procedures
  • Humans
  • Luteinizing Hormone / blood
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / surgery
  • Ovary / surgery
  • Puberty, Precocious / diagnosis*
  • Puberty, Precocious / etiology
  • Puberty, Precocious / surgery
  • Sex Cord-Gonadal Stromal Tumors / complications
  • Sex Cord-Gonadal Stromal Tumors / diagnosis*
  • Sex Cord-Gonadal Stromal Tumors / surgery
  • Testosterone / blood

Substances

  • Estrogens
  • Testosterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone