Combined endovascular and surgical resection of a giant lumbosacral arteriovenous malformation in a patient with Cobb syndrome

J Neurointerv Surg. 2011 Sep;3(3):293-6. doi: 10.1136/jnis.2010.002972. Epub 2011 Apr 6.

Abstract

Objective and importance: Cobb syndrome is a rare condition that includes a cutaneous nevus with an associated spinal vascular lesion at the same dermatome. We present a challenging case of a progressively symptomatic massive lumbosacral arteriovenous malformation (AVM) in a patient with Cobb's syndrome requiring a multimodality approach including staged preoperative transarterial and transvenous endovascular embolization followed by surgical excision and wound reconstruction.

Clinical presentation: The patient presented with a massive lumbosacral AVM with symptoms of congestive heart failure. Angiography demonstrated arterial feeders predominantly from internal iliac, median sacral and lumbar segmental arteries.

Intervention: The patient underwent staged transarterial and transvenous endovascular embolization resulting in 90% reduction in the AVM size, followed by surgical resection of the lesion. The patient made an excellent recovery with improvement in his symptoms of congestive heart failure.

Conclusion: The treatment algorithm for massive AVMs must be individualized. A combination of staged embolization and subsequent surgery may be required to obtain a good result. Through this carefully planned multidisciplinary approach a previously incurable lesion in this patient with Cobb syndrome was able to be treated successfully.

Publication types

  • Case Reports

MeSH terms

  • Arteriovenous Malformations / complications
  • Arteriovenous Malformations / diagnostic imaging
  • Arteriovenous Malformations / surgery
  • Arteriovenous Malformations / therapy*
  • Combined Modality Therapy
  • Embolization, Therapeutic* / methods
  • Humans
  • Lumbosacral Region / blood supply*
  • Nevus / complications*
  • Radiography
  • Skin Neoplasms / complications*
  • Syndrome