Neighborhood-preserving visualization of adaptive structure-activity landscapes: application to drug discovery

Angew Chem Int Ed Engl. 2011 Dec 2;50(49):11633-6. doi: 10.1002/anie.201105156. Epub 2011 Oct 7.

Authors

Michael Reutlinger¹, Wolfgang Guba, Rainer E Martin, Alexander I Alanine, Torsten Hoffmann, Alexander Klenner, Jan A Hiss, Petra Schneider, Gisbert Schneider

Affiliation

¹ Department of Chemistry and Applied Biosciences, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland.

PMID: 21984024
DOI: 10.1002/anie.201105156

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Discovery / methods*
Humans
Models, Biological
Probability
Receptors, Somatostatin / antagonists & inhibitors*
Receptors, Somatostatin / metabolism
Structure-Activity Relationship*

Substances

Receptors, Somatostatin
somatostatin receptor 5