[Extremely prolonged neuromuscular block after a single dose of rocuronium]

O Menouni; A-C Brillouet-Banchereau; G Galan; A Lélias; A Sautereau; S Gadrey

doi:10.1016/j.annfar.2011.07.009

[Extremely prolonged neuromuscular block after a single dose of rocuronium]

Ann Fr Anesth Reanim. 2011 Nov;30(11):841-3. doi: 10.1016/j.annfar.2011.07.009. Epub 2011 Oct 7.

[Article in French]

Authors

O Menouni¹, A-C Brillouet-Banchereau, G Galan, A Lélias, A Sautereau, S Gadrey

Affiliation

¹ Service d'anesthésie, hôpitaux de Bordeaux, CHU de Bordeaux, 12, rue Dubernat, 33404 Talence, France. omarzzine@hotmail.com

PMID: 21983058
DOI: 10.1016/j.annfar.2011.07.009

Abstract

Postoperative curarization in patients has been established. Nevertheless, extremely prolonged neuromuscular blockades are rare. We report the case of a prolonged neuromuscular blockade (lasting 10 hours) following a single dose of rocuronium, in an elderly patient with severe renal failure. We have studied the possible causes of prolonged curarization, and discussed the interest of the use of sugammadex in such cases.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Androstanols / administration & dosage
Androstanols / adverse effects*
Androstanols / antagonists & inhibitors
Diabetes Mellitus, Type 2 / complications
Female
Humans
Kidney Failure, Chronic / complications
Neuromuscular Blockade / adverse effects*
Neuromuscular Nondepolarizing Agents / administration & dosage
Neuromuscular Nondepolarizing Agents / adverse effects*
Neuromuscular Nondepolarizing Agents / antagonists & inhibitors
Postoperative Complications / chemically induced*
Rocuronium
Sugammadex
gamma-Cyclodextrins / therapeutic use

Substances

Androstanols
Neuromuscular Nondepolarizing Agents
gamma-Cyclodextrins
Sugammadex
Rocuronium