Ag cluster-aptamer hybrid: specifically marking the nucleus of live cells

Chem Commun (Camb). 2011 Nov 21;47(43):11960-2. doi: 10.1039/c1cc14652a. Epub 2011 Sep 30.

Abstract

Silver cluster-aptamer hybrids were mineralized via an artificially designed aptamer. The hybrids gave red emission when excited by light, and they successfully targeted the nucleus of live cells. This method is an effective approach to make cell target probes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry*
  • Benzimidazoles / chemistry
  • Cell Line
  • Cell Nucleus / chemistry
  • Cell Nucleus / pathology*
  • Humans
  • Microscopy, Confocal
  • SELEX Aptamer Technique
  • Silver / chemistry*

Substances

  • Aptamers, Nucleotide
  • Benzimidazoles
  • Silver
  • bisbenzimide ethoxide trihydrochloride