Abstract
Despite the apparent simplicity:
of the xanthene fluorophores, the preparation of caged derivatives with free carboxy groups remains a synthetic challenge. A straightforward and flexible strategy for preparing rhodamine and fluorescein derivatives was developed using reduced, “leuco” intermediates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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3T3 Cells
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Animals
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Cell Nucleus / ultrastructure
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Contrast Media / chemical synthesis*
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Contrast Media / chemistry
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Contrast Media / radiation effects
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Fluorescent Dyes / chemical synthesis*
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Fluorescent Dyes / chemistry
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Fluorescent Dyes / radiation effects
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Mice
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Microscopy, Fluorescence
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Molecular Structure
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Photochemistry
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Xanthines / chemical synthesis*
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Xanthines / chemistry
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Xanthines / radiation effects
Substances
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Contrast Media
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Fluorescent Dyes
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Xanthines