Abstract
A generic human papillomavirus (HPV) probe assay was compared to the Linear Array to detect HPV DNA in 1,013 clinical specimens. The sensitivity, specificity, and negative predictive value of the assay were 99.5% (95% confidence interval [CI], 98.4% to 99.9%), 58.6% (95% CI, 53.9% to 63.1%), and 98.9% (95% CI, 96.5% to 99.8%), respectively. This assay conveniently identifies HPV-positive specimens.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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DNA, Viral / genetics
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Female
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Humans
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Male
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Papillomaviridae / classification*
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Papillomaviridae / genetics
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Papillomaviridae / isolation & purification*
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Papillomavirus Infections / diagnosis*
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Papillomavirus Infections / virology*
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Polymerase Chain Reaction / methods*
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Predictive Value of Tests
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Sensitivity and Specificity
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Virology / methods*