Challenges to the development of new agents for molecularly defined patient subsets: lessons from BRCA1/2-associated breast cancer

J Clin Oncol. 2011 Nov 10;29(32):4224-6. doi: 10.1200/JCO.2011.36.8134. Epub 2011 Sep 19.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / genetics
  • Enzyme Inhibitors / therapeutic use*
  • Female
  • Genes, BRCA1*
  • Genes, BRCA2*
  • Humans
  • Mutation*
  • Poly(ADP-ribose) Polymerase Inhibitors*
  • Research Design

Substances

  • Enzyme Inhibitors
  • Poly(ADP-ribose) Polymerase Inhibitors