Urinary incontinence following deep brain stimulation of the pedunculopontine nucleus

Iciar Aviles-Olmos; Thomas Foltynie; Jalesh Panicker; Dorothy Cowie; Patricia Limousin; Marwan Hariz; Clare J Fowler; Ludvic Zrinzo

doi:10.1007/s00701-011-1155-6

Urinary incontinence following deep brain stimulation of the pedunculopontine nucleus

Acta Neurochir (Wien). 2011 Dec;153(12):2357-60. doi: 10.1007/s00701-011-1155-6. Epub 2011 Sep 17.

Authors

Iciar Aviles-Olmos¹, Thomas Foltynie, Jalesh Panicker, Dorothy Cowie, Patricia Limousin, Marwan Hariz, Clare J Fowler, Ludvic Zrinzo

Affiliation

¹ Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. i.olmos@ion.ucl.ac.uk

PMID: 21927820
DOI: 10.1007/s00701-011-1155-6

Abstract

Low-frequency deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been reported to improve akinesia and gait difficulties in patients with Parkinson's disease (PD). We report on a patient with PD and L: -dopa refractory gait symptoms who developed detrusor over-activity immediately after right PPN DBS. Proximity between caudal PPN and brainstem structures implicated in control of micturition is a possible explanation.

Publication types

Case Reports

MeSH terms

Aged
Deep Brain Stimulation / adverse effects*
Deep Brain Stimulation / instrumentation
Deep Brain Stimulation / methods
Humans
Intraoperative Complications / etiology
Intraoperative Complications / physiopathology*
Male
Parkinson Disease / physiopathology
Parkinson Disease / therapy*
Pedunculopontine Tegmental Nucleus / physiopathology
Pedunculopontine Tegmental Nucleus / surgery*
Urinary Incontinence / etiology*
Urinary Incontinence / physiopathology
Urination / physiology*