For patients with terminal pulmonary fibrosis unilateral lung transplantation offers a new therapeutic option. At the Hannover Medical School 5 patients have been successfully treated by single lung transplantation. In 3 patients a left, and in 2 patients a right lung transplant was performed. One patient required intraoperative support by cardiopulmonary bypass. Bronchial omentopexy was used in all instances. Currently all patients are alive. A marked improvement of pulmonary function parameters was seen in all cases. The patients are all able to lead a normal life.