Improved assessment of control in intermittent exotropia using multiple measures

Am J Ophthalmol. 2011 Nov;152(5):872-6. doi: 10.1016/j.ajo.2011.05.007. Epub 2011 Aug 16.

Abstract

Purpose: To develop and validate an improved measure of control in intermittent exotropia (XT).

Design: Prospective, noninterventional case series.

Methods: Twelve children with intermittent XT were evaluated during 4 sessions (2 hours apart) over a day, on 2 separate days (8 sessions per child). Control was standardized using a scoring system and quantified 3 times during each examination. Overall control for a day was calculated as the mean of all 12 measures. Single measures of control and the mean of 2 (double) and 3 (triple) measures over the examination were compared with the respective day mean, and first-day measures were compared to the second-day mean.

Results: At distance, 17% (49/287, 95% confidence interval [CI] 13% to 22%) of single measures differed from the day mean, whereas only 8% (16/191, 95 CI 5% to 13%) of double measures and 5% (5/95, 95% CI 2% to 12%) of triple measures differed. Comparing day 1 measures to overall mean for day 2, 17% (24/143, 95% CI 11% to 24%) of single measures and 17% (22/130, 95% CI 11% to 24%) of double measures differed by more than 1 level, whereas 11% (5/47, 95% CI 4% to 23%) of triple measures differed.

Conclusions: The mean of 3 assessments of control during a clinic examination better represents overall control than a single measure.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adolescent
  • Child
  • Exotropia / physiopathology*
  • Female
  • Fixation, Ocular / physiology*
  • Humans
  • Male
  • Oculomotor Muscles / physiopathology*
  • Prospective Studies
  • Vision, Binocular / physiology*
  • Visual Acuity / physiology