Optimizing the matching between the acid and the base of cooperative catalysis to inhibit dehydration in the aldol condensation

Bo Liu; Shujie Wu; Xiaofang Yu; Jingqi Guan; Qiubin Kan

doi:10.1016/j.jcis.2011.06.068

Optimizing the matching between the acid and the base of cooperative catalysis to inhibit dehydration in the aldol condensation

J Colloid Interface Sci. 2011 Oct 15;362(2):625-8. doi: 10.1016/j.jcis.2011.06.068. Epub 2011 Jul 7.

Authors

Bo Liu¹, Shujie Wu, Xiaofang Yu, Jingqi Guan, Qiubin Kan

Affiliation

¹ College of Chemistry, Jilin University, Changchun 130023, PR China.

PMID: 21803365
DOI: 10.1016/j.jcis.2011.06.068

Abstract

A series of acid-base bifunctional catalysts were prepared, and high yields and excellent selectivity in the aldol condensation were achieved through adjustment of the matching between the acid and the base. The results indicated that proper matching between the acid and the base can both efficiently activate the substrate through cooperative activation and inhibit dehydration without diminishing the yield.