Abstract
In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Antigens, Viral / analysis
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Brain / virology
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Encephalitis, Viral / veterinary*
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Encephalitis, Viral / virology
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Fatal Outcome
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Immunohistochemistry
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Male
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Oligonucleotide Array Sequence Analysis
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Reverse Transcriptase Polymerase Chain Reaction
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Sequence Analysis, DNA
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Texas
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West Nile Fever / diagnosis
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West Nile Fever / veterinary*
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West Nile Fever / virology
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West Nile virus / classification
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West Nile virus / genetics
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West Nile virus / immunology
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West Nile virus / isolation & purification*
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Whale, Killer / virology*