The purpose of this study is to elucidate the relationship among RR interval (RR), the optimal reconstruction phase, and adequate temporal resolution (TR) to obtain coronary CT angiography images of acceptable quality using 64-MDCT (Aquilion 64) of end-systolic reconstruction in 407 patients with high heart rates. Image quality was classified into 3 groups [rank A (excellent): 161, rank B (acceptable): 207, and rank C (unacceptable): 39 patients]. The optimal absolute phase (OAP) significantly correlated with RR [OAP (ms)=119-0.286RR (ms), r=0.832, p<0.0001], and the optimal relative phase (ORP) also significantly correlated with RR [ORP (%)=62-0.023RR (ms), r=0.656, p<0.0001], and the correlation coefficient of OAP was significantly (p<0.0001) higher than that of ORP. The OAP range (±2SD) in which it is highly possible to get a static image was from [119-0.286RR (ms)-46] to [119-0.286RR (ms)+46]. The TR was significantly different among ranks A (97 ± 22 ms), B (111 ± 31 ms) and C (135 ± 34 ms). The TR significantly correlated with RR in ranks A (TR=-16+0.149RR, r=0.767, p<0.0001), B (TR=-15+0.166RR, r=0.646, p<0.0001), and C (TR=52+0.117RR, r=0.425, p=0.0069). Rank C was distinguished from ranks A or B by linear discriminate analysis (TR=-46+0.21RR), and the discriminate rate was 82.6%. In conclusion, both the OAP and adequate TR depend on RR, and the OAP range (±2SD) can be calculated using the formula [119-0.286RR (ms)-46] to [119-0.286RR (ms)+46], and an adequate TR value would be less than (-46+0.21RR).