Abstract
Everolimus-eluting stents and paclitaxel-coated balloons are used in the interventional treatment of coronary artery disease in adults to reduce the restenosis rate and in small-vessel disease. Both substances are released into the circulation. We report systemic drug exposure after implantation of one everolimus-eluting stent and dilation with one paclitaxel-coated balloon in an 8-month-old infant, which was used as an innovative therapy for recurrent pulmonary vein stenosis.
MeSH terms
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Angiography
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Angioplasty, Balloon, Coronary / methods*
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Drug-Eluting Stents*
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Everolimus
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Follow-Up Studies
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Humans
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Immunosuppressive Agents / pharmacokinetics
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Infant, Newborn
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Male
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Paclitaxel / pharmacokinetics*
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Pulmonary Veins / abnormalities*
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Pulmonary Veins / diagnostic imaging
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Pulmonary Veins / surgery
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Pulmonary Veno-Occlusive Disease / blood*
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Pulmonary Veno-Occlusive Disease / congenital
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Pulmonary Veno-Occlusive Disease / surgery
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Recurrence
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Sirolimus / analogs & derivatives*
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Sirolimus / pharmacokinetics
Substances
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Immunosuppressive Agents
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Everolimus
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Paclitaxel
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Sirolimus