The remarkable evolutionary history of endornaviruses

J Gen Virol. 2011 Nov;92(Pt 11):2674-2678. doi: 10.1099/vir.0.034702-0. Epub 2011 Jul 20.

Abstract

The family Endornaviridae contains several members from diverse hosts, including plants, fungi and oomycetes. They are found as large dsRNA elements with a nick in the coding strand. All members encode a conserved RNA-dependent RNA polymerase, but no other domain that is conserved among all members. Based on the conserved domain database comparison the various domains have different origins, indicating a highly modular evolutionary history. In some cases, domains with similar putative functions are found that are derived from different protein families, indicating convergent evolution for a required function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Conserved Sequence
  • Evolution, Molecular*
  • Fungi / virology*
  • Genome, Viral
  • Molecular Sequence Data
  • Oomycetes / virology*
  • Plants / virology*
  • RNA Viruses / genetics*
  • RNA-Dependent RNA Polymerase / genetics
  • Viral Proteins / genetics
  • Viruses

Substances

  • Viral Proteins
  • RNA-Dependent RNA Polymerase