Predicting the future development of depression or PTSD after injury

Gen Hosp Psychiatry. 2011 Jul-Aug;33(4):327-35. doi: 10.1016/j.genhosppsych.2011.05.003. Epub 2011 Jun 15.

Abstract

Objective: The objective was to develop a predictive screener that when given soon after injury will accurately differentiate those who will later develop depression or posttraumatic stress disorder (PTSD) from those who will not.

Method: This study used a prospective, longitudinal cohort design. Subjects were randomly selected from all injured patients in the emergency department; the majority was assessed within 1 week postinjury with a short predictive screener, followed with in-person interviews after 3 and 6 months to determine the emergence of depression or PTSD within 6 months after injury.

Results: A total of 192 completed a risk factor survey at baseline; 165 were assessed over 6 months. Twenty-six subjects [15.8%, 95% confidence interval (CI) 10.2-21.3] were diagnosed with depression, four (2.4%, 95% CI 0.7-5.9) with PTSD and one with both. The final eight-item predictive screener was derived; optimal cutoff scores were ≥2 (of 4) depression risk items and ≥3 (of 5) PTSD risk items. The final screener demonstrated excellent sensitivity and moderate specificity both for clinically significant symptoms and for the diagnoses of depression and PTSD.

Conclusions: A simple screener that can help identify those patients at highest risk for future development of PTSD and depression postinjury allows the judicious allocation of costly mental health resources.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cohort Studies
  • Depression / etiology*
  • Female
  • Forecasting
  • Health Surveys
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Assessment
  • Stress Disorders, Post-Traumatic / etiology*
  • United States
  • Wounds and Injuries / psychology*
  • Young Adult