Chronic actinic dermatitis in Asian skin: a Singaporean experience

Photodermatol Photoimmunol Photomed. 2011 Aug;27(4):172-5. doi: 10.1111/j.1600-0781.2011.00589.x.

Abstract

Background/purpose: To study the characteristics of chronic actinic dermatitis (CAD) in a heterogeneous group of Singaporean patients.

Methods: The photobiologicial features of all patients phototested and diagnosed with CAD from January 2005 to December 2009 were examined retrospectively.

Results: Fifty-eight patients were diagnosed as having CAD. The mean age at diagnosis was 62 years (range 35-83). Forty-one were (70.7%) Chinese, six (10.3%) Indians, eight (13.8%) Malays, and three (5.2%) Others. Forty-seven were (81.0%) male and 11 (19.0%) were female. Forty-nine (84.5%) had Fitzpatrick skin phototype IV and nine (15.5%) had phototype V. Three of 26 (11.5%) tested for human immunodeficiency virus were positive. The face, neck, and forearms were most commonly affected. Thirty-two patients (55.2%) had reduced minimal erythema dose (MED) to both ultraviolet B (UVB)and ultraviolet A (UVA), 23 patients (39.7%) had lowered MED to UVB only, while three (5.1%) had reduced MED to UVA only. Patients were followed up for a mean of 16.8 months. All were treated with photoprotection and topical steroids; however, a few required oral immunosuppression with partial improvement.

Conclusion: In Singapore, CAD was seen more commonly in elderly Chinese males of Fitzpatrick skin phototype IV. Reduced MED to both UVB and UVA was the most common phototest finding.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Asian People
  • Female
  • Follow-Up Studies
  • HIV
  • HIV Infections / epidemiology
  • HIV Infections / ethnology
  • HIV Infections / pathology
  • Humans
  • Male
  • Middle Aged
  • Photosensitivity Disorders* / epidemiology
  • Photosensitivity Disorders* / ethnology
  • Photosensitivity Disorders* / pathology
  • Photosensitivity Disorders* / therapy
  • Retrospective Studies
  • Sex Factors
  • Singapore / epidemiology
  • Singapore / ethnology
  • Skin / pathology
  • Ultraviolet Rays / adverse effects*