Malignant phosphaturic mesenchymal tumor of the larynx

Laryngoscope. 2011 Sep;121(9):1860-3. doi: 10.1002/lary.21916. Epub 2011 Jun 30.

Abstract

Phosphaturic mesenchymal tumors are rare neoplasms predominantly originating in the trunk and extremities. Malignant variants are exceedingly rare, and can present significant diagnostic challenges to the pathologist and otolaryngologist alike. This report describes the first case of malignant phosphaturic mesenchymal tumor involving the larynx, and emphasizes the importance of vigilance in both histopathologic and clinical actions so that appropriate treatment can be provided in a timely manner. The clinical presentation, radiologic and histologic features, and management are discussed.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Humans
  • Hypophosphatemia / diagnosis*
  • Laryngeal Neoplasms / diagnosis*
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / surgery*
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / pathology
  • Liver Neoplasms / surgery*
  • Mesenchymoma / diagnosis*
  • Mesenchymoma / pathology
  • Mesenchymoma / surgery*
  • Osteomalacia / diagnosis
  • Osteomalacia / surgery
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / pathology
  • Paraneoplastic Syndromes / surgery*
  • Young Adult

Supplementary concepts

  • Malignant mesenchymal tumor