Segregation patterns of endogenous mouse mammary tumor viruses in five recombinant inbred strain sets

J Virol. 1990 Sep;64(9):4568-72. doi: 10.1128/JVI.64.9.4568-4572.1990.

Abstract

We identified mouse mammary tumor proviral loci in the AKR/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J, and SWR/J inbred mouse strains and determined their segregation patterns in the AKXD, AKXL, BXD, BXH, and SWXL recombinant inbred strain sets. Two new Mtv loci, Mtv-29 and Mtv-30, were identified. Mtv-30 was genetically mapped to chromosome 12. Additionally, two previously identified Mtv loci, Mtv-14 and Mtv-23, were genetically mapped to chromosome 4 and chromosome 6, respectively.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blotting, Southern
  • Crosses, Genetic
  • DNA, Viral / genetics
  • DNA, Viral / isolation & purification*
  • Genetic Linkage
  • Mammary Tumor Virus, Mouse / genetics
  • Mammary Tumor Virus, Mouse / isolation & purification*
  • Mice
  • Mice, Inbred Strains / microbiology*
  • Nucleic Acid Hybridization
  • Proviruses / genetics
  • Proviruses / isolation & purification
  • Recombination, Genetic
  • Species Specificity

Substances

  • DNA, Viral