Abstract
In an analysis of methicillin-resistant Staphylococcus aureus (MRSA) infected patients treated with arbekacin (ABK) only, Gram-negative bacteria (GNB) that were inhibited by low minimal inhibitory concentrations (MICs) of amikacin (AMK) or gentamycin (GM) were eradicated by the end of the ABK treatment. On the other hand, GNB that were only inhibited by high MICs of AMK or GM persisted until the end of treatment with ABK only. Thus, ABK can be expected to be effective even in cases of mixed infection with GNB and MRSA.
MeSH terms
-
Adult
-
Aged
-
Aged, 80 and over
-
Anti-Bacterial Agents / therapeutic use*
-
Coinfection / drug therapy
-
Coinfection / microbiology*
-
Dibekacin / analogs & derivatives*
-
Dibekacin / therapeutic use
-
Female
-
Gram-Negative Bacteria / drug effects*
-
Gram-Negative Bacteria / isolation & purification
-
Gram-Negative Bacterial Infections / drug therapy
-
Gram-Negative Bacterial Infections / microbiology*
-
Humans
-
Male
-
Methicillin-Resistant Staphylococcus aureus / drug effects
-
Microbial Sensitivity Tests
-
Middle Aged
-
Staphylococcal Infections / drug therapy
-
Staphylococcal Infections / microbiology*
Substances
-
Anti-Bacterial Agents
-
Dibekacin
-
arbekacin