Perioperative management of children with encephalocele: an institutional experience

J Neurosurg Anesthesiol. 2011 Oct;23(4):352-6. doi: 10.1097/ANA.0b013e31821f93dc.

Abstract

Background: Encephaloceles are neural tube defects that are characterized by protrusion of the brain and meninges through a defect in the cranium. The inherent implications of pediatric anesthesia and difficult airway make surgical correction challenging for anesthesiologists

Methods: Available medical records of 118 children who underwent excision and repair of encephalocele over a period of 10 years were analyzed retrospectively. Data on associated anomalies, anesthetic management, perioperative complications, and outcome at discharge were reviewed.

Results: The average age of presentation was 1 year and 6 months. The most common site of lesion was the occiput (67%). Encephaloceles were giant (size of sac larger than the head) in 15.3% of children. Hydrocephalus was the most common complication (45.8%) and was predominantly associated in children with occipital encephaloceles (P=0.00). Difficult mask ventilation and intubation were encountered in 5.9% and 19.5% of children, respectively. In children with occipital encephalocele, the trachea was intubated commonly by direct laryngoscopy in the lateral position (47.5%). The average blood loss was 69.6±13.2 mL, and 56 children required transfusion, the average being 13.2±9.6 mL/kg. Intraoperative hemodynamic disturbances and respiratory complications were observed in 21.1% and 13.5% of children, respectively. The mean intensive care unit and hospital stay were 1.8±2.1 and 8.6±4.9 days, respectively. The stays were prolonged significantly whenever the children developed hydrocephalus, meningitis, and respiratory infection, predisposing to poor outcome.

Conclusions: Difficult airway is not the only concern in children with encephalocele, but associated congenital malformations, hydrocephalus, large size of sac, and hemodynamic disturbances all require careful consideration.

MeSH terms

  • Anesthesia
  • Brain / abnormalities
  • Child
  • Child, Preschool
  • Encephalocele / surgery*
  • Female
  • Heart Diseases / therapy
  • Humans
  • Infant
  • Infant, Newborn
  • Intraoperative Complications / therapy
  • Male
  • Perioperative Care*
  • Postoperative Care
  • Postoperative Complications / therapy
  • Respiration, Artificial
  • Respiratory Mechanics / physiology
  • Retrospective Studies
  • Treatment Outcome