Triple synchronous primary gynecologic carcinomas: a case report and review of the literature

Int J Surg Pathol. 2011 Aug;19(4):552-5. doi: 10.1177/1066896911409579. Epub 2011 Jun 1.

Abstract

Double synchronous primaries are known to occasionally occur in gynecologic cancers. Cases of triple or quadruple synchronous primaries, with only 4 case reports in the literature, are extremely rare. The authors report the case of a 49-year-old para 2-0-0-2 woman who presented for surgical management of metastatic ovarian adenocarcinoma diagnosed at an outside institution. On examination of the surgical specimen, 3 synchronous primary carcinomas with multiple histologic features were identified within the ovaries, uterus, and cervix. Although rare, the possibility of triple synchronous primary malignancies should be considered when evaluating gynecologic malignancies.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Female
  • Humans
  • Middle Aged
  • Neoplasms, Multiple Primary*
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / surgery