Introduction: Microwave ablation (MWA) uses non-ionising thermal energy to cause cell death by coagulative necrosis. Colour Doppler ultrasound (US) produces a spherical image during tissue ablation that appears to approximate the microwave near field (MNF) in shape and size. The aim of the present study was to determine whether colour Doppler US images observed during microwave ablation correlate with the actual thermocoagulation zone (TCZ) observed in liver tissue.
Methods: Twenty MWAs were performed in ex vivo bovine liver using a 915-MHz ablation antenna set to 45 W for 6 min concomitant with Doppler US imaging. The edges of spherical images observed with colour Doppler US were marked circumferentially in the tissue. The tissue was transected parallel to the angle of antenna insertion, and the distances between methylene blue markings and the TCZ were measured.
Results: The images observed using colour Doppler US were similar in size and shape to the actual TCZ observed in the tissue. The mean distance between the observed colour Doppler US field diameter and the measured TCZ was 2 ± 1 mm.
Conclusions: Using colour Doppler US, the visualised field during MWA correlates with the TCZ in an ex vivo bovine liver model. Real-time, dynamic feedback of the treatment area may increase the effectiveness of MWA for liver tumours in vivo.
© 2011 International Hepato-Pancreato-Biliary Association.