Imaging single cells in the living retina

Vision Res. 2011 Jul 1;51(13):1379-96. doi: 10.1016/j.visres.2011.05.002. Epub 2011 May 10.

Abstract

A quarter century ago, we were limited to a macroscopic view of the retina inside the living eye. Since then, new imaging technologies, including confocal scanning laser ophthalmoscopy, optical coherence tomography, and adaptive optics fundus imaging, transformed the eye into a microscope in which individual cells can now be resolved noninvasively. These technologies have enabled a wide range of studies of the retina that were previously impossible.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Humans
  • Microscopy, Confocal
  • Ophthalmoscopy / methods*
  • Retina / pathology*
  • Retinal Cone Photoreceptor Cells / pathology*
  • Retinal Vessels / pathology*
  • Tomography, Optical Coherence