[Growth hormone therapy in adult patients: a review]

Wien Klin Wochenschr. 2011 May;123(9-10):259-67. doi: 10.1007/s00508-011-1574-7. Epub 2011 May 18.
[Article in German]

Abstract

Growth hormone deficiency (GHD) can frequently be expected in hypopituitarism of adult patients. If GHD is proven by dynamic testing of the somatotrophic axis, growth hormone substitution is useful for improving quality of life, body composition, bone and lipid metabolism, and myocardial function according to the criteria of evidence-based medicine and is admitted by most national health authorities. There are no other reasonable indications for growth hormone treatment in adulthood.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adipose Tissue / drug effects
  • Adult
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Bone Density / drug effects
  • Cholesterol, LDL / blood
  • Endothelium, Vascular / drug effects
  • Female
  • Human Growth Hormone / deficiency*
  • Human Growth Hormone / therapeutic use*
  • Humans
  • Hypopituitarism / drug therapy*
  • Hypopituitarism / etiology
  • Hypopituitarism / mortality
  • Hypopituitarism / psychology
  • Lipids / blood
  • Male
  • Middle Aged
  • Myocardial Contraction / drug effects
  • Population Dynamics
  • Quality of Life / psychology
  • Survival Analysis

Substances

  • Cholesterol, LDL
  • Lipids
  • Human Growth Hormone